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Dr. Eleanor Fish (a prominent immunologist at the University of Toronto, Canada) comments that she does not think BCG may completely eliminate infection caused by a novel coronavirus, but it is likely to mitigate the effects of a novel coronavirus on individuals.The scientists involved in the study hope that BCG vaccination may ease the burden on the health system before a specific vaccine for Covid-19 is available.
1.BCG Clinical Trials for Against Covid-19
Researchers in four countries (the Netherlands, Australia, Germany, and the United Kingdom) will soon begin clinical trials of new coronaviruses using unconventional methods.They will test whether a century-old anti-tuberculosis (TB) vaccine (BCG) can broadly improve the body's immune system, making it better able to fight sars-cov-2 and possibly prevent infection altogether.The study will be administered to people at high risk, including physicians and nurses, and to older adults.
A team at the university of Melbourne in Australia is using exactly the same protocol to carry out the BCG study among healthcare workers.Another team at the university of Exeter in the UK will conduct a similar study on older people.Last week, a team at the Max Planck Institute for Infection Biology in Germany announced that, inspired by Netea's work, they would carry out similar clinical trials in older people and healthcare workers with another anti-tb vaccine in development, VPM1002, a genetically modified BCG vaccine."The elderly and health care workers are bearing the brunt of the current outbreak, so they would particularly benefit if the VPM1002 vaccine could help."They said.
2.Introduction of BCG
The BCG vaccine consists of an attenuated (weakened) version of a relative of Mycobacterium tuberculosis, the causative agent of TB. The vaccine is in most countries in the world of children after the birth of the first annual vaccination is used, the BCG vaccine to be both safe and cheap, it can prevent an average of about 60% of TB cases, children vary widely between countries.Vaccines typically produce an immune response against the target pathogen, such as antibodies that bind and neutralize one virus but do not bind to others.But BCG may also enhance the immune system's ability to fight pathogens other than tuberculosis, according to decades of published clinical and observational studies.The researchers concluded that in the first year after vaccination, about 30 percent of all known pathogens, including viruses, could be prevented.A 2014 review by the world health organization concluded that BCG appeared to reduce overall child mortality.
3.BCG can "Train" Innate Immunity
The innate immune system, composed of white blood cells such as macrophages, natural killer cells and neutrophils, should not have this memory.The team, led by professor Netea, found that BCG could survive for months in human skin, stimulating not only the t-cells and b-cells of mycobacterium memoriae, but also the white blood cells responsible for innate immunity, which can quickly respond to new infections.In a randomized placebo-controlled study published in 2018, the team showed that BCG vaccination prevented the yellow fever virus from being experimentally infected.
BCG Vaccine for Prevent Covid-19 Market contains market size and forecasts of BCG Vaccine for Prevent Covid-19 in global, including the following market information:
Global BCG Vaccine for Prevent Covid-19 Market Revenue, 2017-2022, 2023-2028, ($ millions)
Global BCG Vaccine for Prevent Covid-19 Market Sales, 2017-2022, 2023-2028, (K Doses)
Global top five BCG Vaccine for Prevent Covid-19 companies in 2021 (%)
The global BCG Vaccine for Prevent Covid-19 market was valued at million in 2021 and is projected to reach US$ million by 2028, at a CAGR of % during the forecast period.
The U.S. Market is Estimated at $ Million in 2021, While China is Forecast to Reach $ Million by 2028.
by Dosage Segment to Reach $ Million by 2028, with a % CAGR in next six years.
The global key manufacturers of BCG Vaccine for Prevent Covid-19 include Merck, Sanofi Pasteur, Japan BCG Lab, China National Biotec, InterVax, Serum Institute of India, GreenSignal, Statens Serum Institute and Shanyao Group and etc. In 2021, the global top five players have a share approximately % in terms of revenue.
We surveyed the BCG Vaccine for Prevent Covid-19 manufacturers, suppliers, distributors and industry experts on this industry, involving the sales, revenue, demand, price change, product type, recent development and plan, industry trends, drivers, challenges, obstacles, and potential risks.
Total Market by Segment:
Global BCG Vaccine for Prevent Covid-19 Market, by Type, 2017-2022, 2023-2028 ($ Millions) & (K Doses)
Global BCG Vaccine for Prevent Covid-19 Market Segment Percentages, by Type, 2021 (%)
by Dosage
0.5ml Package
1ml Package
2ml Package
Other
by Type of Inoculator
Initial Vaccinate
Revaccination
Global BCG Vaccine for Prevent Covid-19 Market, by Application, 2017-2022, 2023-2028 ($ Millions) & (K Doses)
Global BCG Vaccine for Prevent Covid-19 Market Segment Percentages, by Application, 2021 (%)
0-5 Years Old
5-18 Years Old
18-45 Years Old
45-65 Years Old
?65 Years Old
Global BCG Vaccine for Prevent Covid-19 Market, By Region and Country, 2017-2022, 2023-2028 ($ Millions) & (K Doses)
Global BCG Vaccine for Prevent Covid-19 Market Segment Percentages, By Region and Country, 2021 (%)
North America
US
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Russia
Nordic Countries
Benelux
Rest of Europe
Asia
China
Japan
South Korea
Southeast Asia
India
Rest of Asia
South America
Brazil
Argentina
Rest of South America
Middle East & Africa
Turkey
Israel
Saudi Arabia
UAE
Rest of Middle East & Africa
Competitor Analysis
The report also provides analysis of leading market participants including:
Key companies BCG Vaccine for Prevent Covid-19 revenues in global market, 2017-2022 (Estimated), ($ millions)
Key companies BCG Vaccine for Prevent Covid-19 revenues share in global market, 2021 (%)
Key companies BCG Vaccine for Prevent Covid-19 sales in global market, 2017-2022 (Estimated), (K Doses)
Key companies BCG Vaccine for Prevent Covid-19 sales share in global market, 2021 (%)
Further, the report presents profiles of competitors in the market, key players include:
Merck
Sanofi Pasteur
Japan BCG Lab
China National Biotec
InterVax
Serum Institute of India
GreenSignal
Statens Serum Institute
Shanyao Group
Shanghai Institute of Biological Products
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