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Download Free sampleA buffer solution is comprised of a weak conjugate acid-base pair, for example, a weak acid and its conjugate base, or a weak base and its conjugate acid. Small quantities of other acids or bases are neutralized when added to the solution, and as a result, the solution resists changes in pH. Solutions with stable pH are required for the processing of protein-based biologic APIs because of their sensitivity to changes in pH. The stable pH range and capacity (the amount of acid/base that can be added without a change in pH) of a buffer are determined by the conjugate acid-base pair.
Most purification steps for downstream processing of biologics require buffers to equilibrate, condition, wash, elute, or concentrate the product. They are used in product isolation and purification steps to facilitate protein capture and polishing and also in the filtration process for the removal of viruses or depyrogenation. Aqueous solutions are also required for cleaning and disinfecting downstream processing equipment, such as chromatography matrices and membrane filtration systems. The main equipment involved in downstream processing with buffers includes mixers for buffer preparation, as well as equipment for purification, including packed-bed chromatography systems, fluidized beds, ultrafiltration and diafiltration membranes, microfiltration membranes, depth filtration cartridges, and virus-removal systems.
Bio Pharma Buffer Market contains market size and forecasts of Bio Pharma Buffer in global, including the following market information:
Global Bio Pharma Buffer Market Revenue, 2017-2022, 2023-2028, ($ millions)
Global Bio Pharma Buffer Market Sales, 2017-2022, 2023-2028, (K Liter)
Global top five Bio Pharma Buffer companies in 2021 (%)
The global Bio Pharma Buffer market was valued at 865.8 million in 2021 and is projected to reach US$ 1380.3 million by 2028, at a CAGR of 6.9% during the forecast period.
The U.S. Market is Estimated at $ Million in 2021, While China is Forecast to Reach $ Million by 2028.
Phosphates Type Segment to Reach $ Million by 2028, with a % CAGR in next six years.
The global key manufacturers of Bio Pharma Buffer include Avantor, Alfa Aesar (Thermo Fisher), Merck, Lonza, Bio-Rad, BD, GE Healthcare, Promega Corporation and Hamilton Company, etc. In 2021, the global top five players have a share approximately % in terms of revenue.
We surveyed the Bio Pharma Buffer manufacturers, suppliers, distributors and industry experts on this industry, involving the sales, revenue, demand, price change, product type, recent development and plan, industry trends, drivers, challenges, obstacles, and potential risks.
Total Market by Segment:
Global Bio Pharma Buffer Market, by Type, 2017-2022, 2023-2028 ($ Millions) & (K Liter)
Global Bio Pharma Buffer Market Segment Percentages, by Type, 2021 (%)
Phosphates Type
Acetates Type
TRIS Type
Others
Global Bio Pharma Buffer Market, by Application, 2017-2022, 2023-2028 ($ Millions) & (K Liter)
Global Bio Pharma Buffer Market Segment Percentages, by Application, 2021 (%)
Research Institution
Pharmaceutical Industry
Others
Global Bio Pharma Buffer Market, By Region and Country, 2017-2022, 2023-2028 ($ Millions) & (K Liter)
Global Bio Pharma Buffer Market Segment Percentages, By Region and Country, 2021 (%)
North America
US
Canada
Mexico
Europe
Germany
France
U.K.
Italy
Russia
Nordic Countries
Benelux
Rest of Europe
Asia
China
Japan
South Korea
Southeast Asia
India
Rest of Asia
South America
Brazil
Argentina
Rest of South America
Middle East & Africa
Turkey
Israel
Saudi Arabia
UAE
Rest of Middle East & Africa
Competitor Analysis
The report also provides analysis of leading market participants including:
Key companies Bio Pharma Buffer revenues in global market, 2017-2022 (Estimated), ($ millions)
Key companies Bio Pharma Buffer revenues share in global market, 2021 (%)
Key companies Bio Pharma Buffer sales in global market, 2017-2022 (Estimated), (K Liter)
Key companies Bio Pharma Buffer sales share in global market, 2021 (%)
Further, the report presents profiles of competitors in the market, key players include:
Avantor
Alfa Aesar (Thermo Fisher)
Merck
Lonza
Bio-Rad
BD
GE Healthcare
Promega Corporation
Hamilton Company
XZL BIO-TECHNOLOGY
SRL
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